POS-004 HYPOALBUMINEMIA AND ACUTE KIDNEY INJURY IN PATIENTS ADMITTED TO INTENSIVE CARE UNIT

Acute kidney injury (AKI) is a disease of diverse etiology, consisting decrease in the glomerular filtration rate and therefore with retention waste products such as urea creatinine, accompanied by fluid, electrolyte acid-base disorders. It present 39.5% cases admitted to intensive care unit (ICU) our hospital, it affects mainly men infectious processes, impacting mortality. Hypoalbuminemia has been associated positive fluid balances, however there are few studies that attempt associate AKI. Case-control study, including patients ICU at Hospital Central Sur de Alta Especialidad (HCSAE) Mexico City serum albumin determination admittance. The were distributed into control group (normoalbuminemia >3.5 g/dl) studied (hypoalbuminemia <3.5 g/dl). Patients on hemodialysis, peritoneal dialysis, transplant, burned patients, fed parental nutrition, liver failure excluded. Those who presented two AKI events less than 7 days eliminated. Statistical analysis was carried out using SPSS software, version 20 (SPSS, Inc., Chicago, IL). A t-test one-way ANOVA used for normally data. Categorical data compared Pearson chi-squared test or Fisher’s exact test. Data not analyzed Mann–Whitney U test, Wilcoxon signed-rank Kruskal–Wallis Continuous variables described mean standard deviation median interquartile range (IQR). P values ≤ 0.05 considered represent statistically significant differences. primary outcome determine whether hypoalbuminemia development ICU. 197 included, 174 study 23 group; (51%) ,median age 71 (+17.41) years. Mortality predominated 160 (92%) vs 16 (69.6%) (p <0.005). more frequent 122 (70.1%) (39.1%) OR 3.01 [95% CI 1.48-8.9; p = 0.004),septic shock 54% <0.0001). Hypoalbuminemic had higher amine requirements [132 (75.9%); 0.001]. ratio acute versus hypoalbuminemia.